On Wednesday, Johnny Depp joined Brad Pitt (1995 and 2000) and George Clooney (1997 and 2006) as the only two-time winners of the much-debated title. It was something of a surprise: Usually, People's sexiest man is coming off a year spent in the public spotlight because of a major movie release. Depp, who won in 2003, breaks the mold, winning despite his keeping a low profile in 2009.

... Others in the Sexiest issue: Gilles Marini; James Marsden; Eddie Cibrian; Hunter Parrish; John Legend; Justin Bartha, the male cast members of TV series Glee; Barack Obama; Nicolas Sarkozy; Vladimir Putin; Zac Efron; Robert Pattinson; Jerry O'Connell; Jon Hamm; Matt Damon; Ryan Reynolds.